정영재

A Novel Applications of Polymerization Based Amplification for Detections

Department of Chemistry
Organic chemistry and Functional Materials Laboratory
Youngjae Jung
Polymer-Based-Amplification (PBA) is an effective way to amplify signals to visually inspect substance of very low concentrations without the expensive equipment and skilled personnel. PBA has been studied for an early diagnosis such as Alzheimer's disease and malaria until now. For an early diagnosis, it has considerable accuracy due to the use of Enzyme-Linked Immunosorbent Assay (ELISA). But, accuracy of ELISA means a limit of a non-selective substance. And in an early diagnosis, dyes that is used in PBA only plays a role only as a radical source in photopolymerization and the part of detection is antigen-antibody. In addition to the role of the radical source, this research also implements the role of detecting the substance, thereby overcoming the limitations of the PBA detection substance and applying the simplified process to improve accessibility, productivity.
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